Pain Management

Pain management is essential because even when the underlying disease process is stable, uncontrolled pain prevents patients from working productively, enjoying recreation, or taking pleasure in their usual roles in the family and society.

Arezou Petrie, RPh

Compounding Specialist

Managing Chronic & Acute Pain Safely and Effectively

Chronic pain may have a myriad of causes and perpetuating factors, and therefore can be much more difficult to manage than acute pain, requiring a multidisciplinary approach and customized treatment protocols to meet the specific needs of each patient. Acute pain may be temporary, but mild to severe crises must be carefully assessed and managed as they occur to prevent recurring pain. Optimal treatment may involve the use of medications that possess pain-relieving properties, including:

anticonvulsants
antidepressants
Antiviral agents
antiarrhythmics
anesthetics
NMDA (N-methyl-D-aspartate) antagonists

NMDA-receptor antagonists, such as dextromethorphan and ketamine, can block pain transmission in dorsal horn spinal neurons, reduce nociception and decrease tolerance to and the need for opioid analgesics.

Topical Pain Medication

By combining various agents which utilize different mechanisms to alter the sensation of pain, physicians have found that smaller concentrations of each medication can be used.

Topical and transdermal creams and gels can be formulated to:

Provide high local concentrations at the site of application

(e.g., NSAIDs for joint pain)

Be applied on trigger points

(e.g., combinations of medications for neuropathic pain)

Incorporate medical ingredients in a base that allows systemic absorption
  • 14248 Oxnard St.
    Suite B
    Van Nuys, CA 91401
  • 833-5RX-LOVE / 818-570-8340
  • Fax: 818-647-6327 / 909-354-3476
  • Email: ecp@exigencyrx.com
  • Monday-Friday 8:00 - 3:00

Have any questions? Call us now!

Side effects associated with oral administration such as drowsiness and nausea can often be avoided when medications are used topically. Studies suggest that there are no great restrictions on the type of drug that can be incorporated into a properly compounded transdermal gel.

When medications are administered transdermally, they are not absorbed through the gastrointestinal system and do not undergo first-pass hepatic metabolism.

Conditions that can benefit from compounded pain medication:

  • Post-surgery recovery
  • Diabetic neuropathy
  • Chronic neurological pain
  • Osteoarthritis
  • Rheumatoid arthritis
  • Knee, shoulder, neck, back pain
  • Sports injuries
  • Fibromyalgia
  • Lupus
  • Carpal tunnel syndrome

Please contact our compounding pharmacist to discuss the dosage form, strength, medication or combination that is most appropriate for your patients.