Arezou Petrie, RPh
Chronic pain may have a myriad of causes and perpetuating factors, and therefore can be much more difficult to manage than acute pain, requiring a multidisciplinary approach and customized treatment protocols to meet the specific needs of each patient. Acute pain may be temporary, but mild to severe crises must be carefully assessed and managed as they occur to prevent recurring pain. Optimal pain management treatment may involve the use of medications that possess pain-relieving properties, including:
NMDA-receptor antagonists, such as dextromethorphan and ketamine, can block pain transmission in dorsal horn spinal neurons, reduce nociception and decrease tolerance to and the need for opioid analgesics.
By combining various agents which utilize different mechanisms to alter the sensation of pain, physicians have found that smaller concentrations of each medication can be used.
Topical and transdermal creams and gels can be formulated to:
(e.g., NSAIDs for joint pain)
(e.g., combinations of medications for neuropathic pain)
Side effects associated with oral administration such as drowsiness and nausea can often be avoided when medications are used topically. Studies suggest that there are no great restrictions on the type of drug that can be incorporated into a properly compounded transdermal gel.
When medications are administered transdermally, they are not absorbed through the gastrointestinal system and do not undergo first-pass hepatic metabolism.
We provide 24/7 live answering service,
along with free delivery within 50 miles*
We treat urgent matters and can have your medication
ready and delivered within 24 hours**
* Free delivery with $65 minimum order, excluding rush deliveries.
** Weekdays only. Refills must be available. Some orders may require more time to process depending on the type of compound(s) needed.